Lv11
8 积分 2025-08-29 加入
Discovered potent bifunctional small molecules targeting DNA-PK and HDAC6, with pharmacokinetic properties superior to those in acute myeloid leukemia treatment
58分钟前
待确认
InhibitWin duo: Rational design and structural insights on dual PARP/HDAC inhibitors for synergistic DNA repair disruption and epigenetic regulation
1小时前
已关闭
Mechanisms of HDAC synergistic antitumor effects with the PD-1/PD-L1 pathway, combination therapy strategies, and advances in dual-target inhibitors
1小时前
已关闭
G9a/GLP modulators: degradant inhibitors
1小时前
已完结
Poly(ADP-ribose)polymerase-1 dual-target inhibitors for cancer treatment: progress, challenges, and opportunities
1小时前
已完结
Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
14天前
已完结
Discovery and Characterization of ZL-2201, a Potent, Highly Selective, and Orally Bioavailable Small-molecule DNA-PK Inhibitor
14天前
已关闭
Developing PD-L1 targeting small molecule immunotherapy enzyme inhibitors for personalized anti-tumor immunotherapy
17天前
已完结
Discovery of Novel Resorcinol Dibenzyl Ethers Targeting the Programmed Cell Death-1/Programmed Death-Ligand 1 Interaction as Potential Anticancer Agents
20天前
已完结
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