Lv1
90 积分 2025-07-29 加入
Dibenzo[ b , f ][1,4]oxazepines and dibenzo[ b , e ]oxepines: Influence of the chlorine substitution pattern on the pharmacology at the H 1 R, H 4 R, 5-HT 2A R and other selected GPCRs
19天前
已完结
Development of APH003─a Highly Potent, Selective, and Orally Bioavailable IRAK4 PROTAC Degrader for the Treatment of Inflammatory Diseases
1个月前
已完结
Inhibition of Kornblum Reaction with Lithium Salts in SN2 Reactions of Sulfonates and a Nucleophile Containing a Pyridine N-Oxide Moiety: Convergent and Selective Synthesis of an MRGPRX2 Antagonist
2个月前
已完结
Furanocoumarin derivatives inhibit MRGPRX2-mediated pseudo-allergy
4个月前
已完结
Discovery of the First α-Amino-3-hydroxy-5-methyl-4-isoxazolepropionic Acid (AMPA) Receptor Antagonist Dependent upon Transmembrane AMPA Receptor Regulatory Protein (TARP) γ-8
5个月前
已完结
6,7-Dihalo-Benzothiadiazines as Potent and Selective AMPA Receptor Modulators for Cognitive Enhancement and Neuroprotection
5个月前
已完结
Mechanisms underlying TARP modulation of the GluA1/2-γ8 AMPA receptor
5个月前
已完结
Examination of Noncanonical Kinase Hinge Binders Leads to Thiadiazoles as Potent IRAK4 Inhibitors
7个月前
已完结
Macrocycles for Conventionally Druggable Targets: Lessons from Macrocyclic Kinase Inhibitors
11个月前
已完结
Discovery of IRAK4 Inhibitors BAY1834845 (Zabedosertib) and BAY1830839
1年前
已完结
皖公网安备34019202002308
