Lv6
1880 积分 2024-06-26 加入
Mechanism‐Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure–Activity Relationship, Biostructural, and Kinetic Insight
10小时前
待确认
SIRT5 safeguards against primate skeletal muscle ageing via desuccinylation of TBK1
5天前
已完结
SIRT5-mediated desuccinylation prevents mitochondrial dysfunction in alveolar epithelial cells senescence and pulmonary fibrosis
5天前
已完结
SIRT5 exacerbates eosinophilic chronic rhinosinusitis by promoting polarization of M2 macrophage
5天前
已完结
An FDA-approved drug library screening identifies proteasome inhibitors as selective cytotoxic agents for angiosarcoma cells
6天前
已关闭
Treatment with senolytic drugs ameliorates steroid-induced osteonecrosis of the femoral head by inhibiting osteoclastogenesis
6天前
已关闭
Tryptophan metabolism as a common therapeutic target in cancer, neurodegeneration and beyond
10天前
已完结
Astrocytic LRP1 enables mitochondria transfer to neurons and mitigates brain ischemic stroke by suppressing ARF1 lactylation
11天前
已完结
ACSL4 promotes microglia-mediated neuroinflammation by regulating lipid metabolism and VGLL4 expression
12天前
已完结
Mechanisms of iron–sulfur protein maturation in mitochondria, cytosol and nucleus of eukaryotes
16天前
已关闭
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