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22 积分 2024-07-09 加入
The design, synthesis and bioactivity evaluation of novel androgen receptor degraders based on hydrophobic tagging
17天前
已完结
ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC
17天前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
17天前
已完结
Arylidene-Thiazoldione Scaffold Acts as the E3 Ligand of DCAF11 for PROTAC Design
21天前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
21天前
已完结
Chemical Proteomics Identifies RBBP7 as a New E3 Ligase Supporting Targeted Protein Degradation
1个月前
已完结
Therapeutic options for extramedullary involvement in multiple myeloma
1个月前
已完结
Designing Chromane Derivatives as α2A-Adrenoceptor Selective Agonists via Conformation Constraint
2个月前
已完结
Design and development of novel EGFR inhibitors spanning all subgroups of EGFR mutations in non-small cell lung cancer
2个月前
已完结
Discovery of Highly Potent CRBN Ligands and Insight into Their Binding Mode through Molecular Docking and Molecular Dynamics Simulations
3个月前
已完结
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