Lv11
28 积分 2024-07-09 加入
DeepDegradome: A structure-aware deep learning framework for PROTAC and ligand generation against protein targets
1小时前
已完结
Nanoscale Immune Activator for Enhancing CD8+ T Cell Infiltration in Hepatocellular Carcinoma
5天前
已完结
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
1个月前
已完结
RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma
2个月前
已完结
TRIM27-Cas9–loaded EVs suppress HCC proliferation and enhance responsiveness to anti–PD-1 therapy by promoting ACSL4-mediated ferroptosis
2个月前
已完结
Targeting YAP-mediated HSC death susceptibility and senescence for treatment of liver fibrosis
2个月前
已完结
Hydrophobic Tag Degraders Overcome Endocrine‐Resistant Breast Cancer by Recruiting HSP27‐Mediated E3 Ligase Complex for ERα Proteasomal Degradation
2个月前
已完结
The design, synthesis and bioactivity evaluation of novel androgen receptor degraders based on hydrophobic tagging
3个月前
已完结
ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC
3个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
3个月前
已完结
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