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4 积分 2024-07-09 加入
RanBP2 promotes ferroptosis resistance and compromises therapeutic response by stabilizing SLC7A1 through LRSAM1 SUMOylation and ubiquitination in lung adenocarcinoma
1个月前
已完结
TRIM27-Cas9–loaded EVs suppress HCC proliferation and enhance responsiveness to anti–PD-1 therapy by promoting ACSL4-mediated ferroptosis
1个月前
已完结
Targeting YAP-mediated HSC death susceptibility and senescence for treatment of liver fibrosis
1个月前
已完结
Hydrophobic Tag Degraders Overcome Endocrine‐Resistant Breast Cancer by Recruiting HSP27‐Mediated E3 Ligase Complex for ERα Proteasomal Degradation
1个月前
已完结
The design, synthesis and bioactivity evaluation of novel androgen receptor degraders based on hydrophobic tagging
2个月前
已完结
ZBTB11 Depletion Targets Metabolic Vulnerabilities in K-Ras Inhibitor Resistant PDAC
2个月前
已完结
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
2个月前
已完结
Arylidene-Thiazoldione Scaffold Acts as the E3 Ligand of DCAF11 for PROTAC Design
2个月前
已完结
GID4-Recruiting PROTACs for BRD4 Degradation Overcome Resistance Driven by CRBN and VHL Deficiency
2个月前
已完结
Chemical Proteomics Identifies RBBP7 as a New E3 Ligase Supporting Targeted Protein Degradation
3个月前
已完结
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