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40 积分 2023-10-19 加入
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
3天前
已完结
Development of RMC-6236, a potent and orally bioavailable RAS(ON) multi-selective tri-complex inhibitor for the treatment of RAS-addicted cancers by targeting multiple RAS variants
1个月前
已关闭
Development of RMC-6236, a potent and orally bioavailable RAS(ON) multi-selective tri-complex inhibitor for the treatment of RAS-addicted cancers by targeting multiple RAS variants
1个月前
已关闭
Structure-Guided Design of ISOX-DUAL-Based Degraders Targeting BRD4 and CBP/EP300: A Case of Degrader Collapse
1个月前
已完结
Discovery and Characterization of RP03707: A Highly Potent and Selective KRASG12D PROTAC
1个月前
已完结
Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras
1个月前
已完结
Design of PROTACs utilizing the E3 ligase GID4 for targeted protein degradation
1个月前
已完结
Discovery of Novel Janus Kinase (JAK) and Histone Deacetylase (HDAC) Dual Inhibitors for the Treatment of Hematological Malignancies
2个月前
已完结
3DSTarPred: A Web Server for Target Prediction of Bioactive Small Molecules Based on 3D Shape Similarity
2个月前
已完结
The MOZ-BRPF1 acetyltransferase complex in epigenetic crosstalk linked to gene regulation, development, and human diseases
2个月前
已完结
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