Lv11
36 积分 2023-10-19 加入
Identification of Novel pan-KRAS Inhibitors via Structure-Based Drug Design, Scaffold Hopping, and Biological Evaluation
6小时前
待确认
A chemical agonist and the Golgi-resident lipid PI4P activate STING by inducing transmembrane helix rearrangement
7天前
已完结
ArfGAP2 promotes STING proton channel activity, cytokine transit, and autoinflammation
27天前
已完结
MISO: microfluidic protein isolation enables single-particle cryo-EM structure determination from a single cell colony
28天前
已完结
Isoform-specific function of NSD3 in DNA replication stress confers resistance to PARP inhibitors in prostate cancer
28天前
已完结
Regulation of cGAS-STING signalling and its diversity of cellular outcomes
29天前
已完结
PRMT5: A Promising Synthetical Lethal Target for MTAP-Deleted Cancers
1个月前
已完结
Lysine-Targeting, Covalent Inhibitors of Bromodomain BD1 of BET Proteins in Live Cells and Animals
1个月前
已完结
PARP7: an Emerging Therapeutic Target-Insights into Biological Functions and Advances in Small-Molecule Inhibitor Development
1个月前
已完结
Application of Hypoxia-Activated Prodrugs in Tumor Therapy: Design Strategies and Perspectives
1个月前
已完结
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