Lv11
42 积分 2023-10-19 加入
Development of Orally Bioavailable Peptides Targeting an Intracellular Protein: From a Hit to a Clinical KRAS Inhibitor
5小时前
待确认
Targeting the H/KRAS α4-β6-α5 Allosteric Lobe with Macrocyclic Peptides
5小时前
已完结
Characterisation of a novel KRAS G12C inhibitor ASP2453 that shows potent anti-tumour activity in KRAS G12C-mutated preclinical models
8天前
已完结
The global, regional, and national burden of cancer, 1990-2023, with forecasts to 2050: a systematic analysis for the Global Burden of Disease Study 2023
13天前
已完结
Discovery of EGT710, an Oral Nonpeptidomimetic Reversible Covalent SARS-CoV‑2 Main Protease Inhibitor
18天前
已完结
Synthesis, biological evaluation, and mechanism investigation of multisubstituted quinazoline analogues as prospective inhibitors of KRAS G12D
19天前
已关闭
Discovery of Potent and Orally Bioavailable Pyrimidine Amide cGAS Inhibitors via Structure-Guided Hybridization
25天前
已完结
Discovery of novel cGAS inhibitors based on natural flavonoids
25天前
已完结
From KRASG12D to Pan-KRAS Inhibitors─A Journey Enabled by Synthetic Innovation and Structure-Based Drug Design
26天前
已完结
Structure-Based Design and Evaluation of Reversible KRAS G13D Inhibitors
28天前
已完结
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