Lv11
74 积分 2021-07-13 加入
Emerging interleukin-1 receptor-associated kinase 4 (IRAK4) inhibitors or degraders as therapeutic agents for autoimmune diseases and cancer
3小时前
待确认
Structure-based discovery of sulfamoyl-ethyl-4-oxo-3,4-dihydro-7H-pyrrolo[2,3-d]pyrimidine amides and sulfonamides as potent B-Cell Lymphoma 6 (BCL6)-BTB inhibitors
14天前
已完结
Cleaner and greener synthesis of 3H-benzothiazole-2-thione and its derivatives
26天前
已完结
Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma
1个月前
已完结
Discovery of the Potent, Selective, Orally Available CXCR7 Antagonist ACT-1004-1239
1个月前
已完结
Effect of a cis-4-Aminopiperidine-3-carboxylic Acid (cis-APiC) Residue on Mixed-helical Folding of Unnatural Peptides
1个月前
已完结
Development of a Scalable, Stereoselective Second-Generation Route for CXCR7 Antagonist ACT-1004-1239 via Chiral Enamine Reduction and a Novel Telescoped Sequence of Transesterification, cis-to-trans Epimerization, and Saponification
1个月前
已完结
Modular PROTAC/IMiD Bifunctional Molecule Design for the Degradation of Synergistic Targets in the Treatment of Lymphoma
1个月前
已完结
Ligand‐Promoted Iron‐Catalyzed Nitrene Transfer for the Synthesis of Hydrazines and Triazanes through N‐Amidation of Arylamines
1个月前
已完结
Development of a Novel B-Cell Lymphoma 6 (BCL6) PROTAC To Provide Insight into Small Molecule Targeting of BCL6
1个月前
已完结