Lv2
178 积分 2024-07-30 加入
Unnatural amino acid-based miniPROTACs enable efficient oncoprotein degradation
12天前
已完结
Design, synthesis and biological evaluation of tyrosinase-targeting PROTACs
23天前
已完结
Hypoxia deactivates epigenetic feedbacks via enzyme-derived clicking proteolysis-targeting chimeras
23天前
已完结
Design and Optimization of Lysosome-Targeted Galactoside Senolytic Prodrugs: Harnessing the Aromatic Ring of Self-Immolative Linkers
25天前
已完结
Ball-Lightning-like Relativistic Terahertz Solitons
25天前
已关闭
Discovery and Evaluation of N -Arylindole-Based GluN2B-NMDAR Antagonists with Reduced Cardiotoxicity for the Treatment of Ischemic Stroke
25天前
已完结
DDDR-26. Preclinical evaluation of first-in-class PROTAC survivin degrader HMAK101 for radiosensitization of CNS malignancies
1个月前
已关闭
Abstract LB236: HP-002: A brain-penetrant PROTAC that demonstrated potent anti-proliferation activities on multiple BTK mutant
1个月前
已关闭
Hijacking ERAD for targeted degradation of transmembrane proteins
1个月前
已完结
Aptamer‐PROTAC Conjugates (APCs) for Tumor‐Specific Targeting in Breast Cancer
1个月前
已完结