Lv11
76 积分 2023-09-15 加入
Discovery ofZJC-11 as a Novel Selective CDK7 Inhibitorfor Treating Triple-Negative Breast Cancer by Inducing Cell Senescence
23分钟前
已完结
HMC ameliorates myocardial ischaemia–reperfusion injury through suppressing cuproptosis via the de‐ubiquitination and stabilization of ATP7A
5天前
已完结
A ROS-Responsive Dual-Functional H2S Donor for Synergistic Cardioprotection
20天前
已完结
Targeting Poly (ADP-ribose) polymerase-1 (PARP-1) for DNA repair mechanism through QSAR-based virtual screening and MD simulation
21天前
已完结
Discovery of a New Scaffold RSK2 Inhibitor With Virtual and Phenotypical Screening
21天前
已完结
Design and synthesis of highly selective Janus kinase 3 covalent inhibitors for the treatment of rheumatoid arthritis
28天前
已完结
Structural optimization and biological evaluation of 5-fluoro-7H-pyrrolo[2,3- d]pyrimidine derivatives as potent FAK inhibitors for the treatment of triple negative breast cancers (TNBC)
1个月前
已完结
Identification of a Potent and Selective Focal Adhesion Kinase Proteolysis Targeting Chimera: Targeting Noncatalytic Functions of Focal Adhesion Kinase to Facilitate Antitumor Immunity
1个月前
已完结
Discovery of a Potent NAMPT-Targeting PROTAC for the Suppression of Triple-Negative Breast Cancer via Macrophage Reprogramming
1个月前
已完结
Discovery of Deuterated 3,4-Dihydro-benzo[ e ][1,4]diazepine-2,5-dione Derivatives as Potent, Selective and Orally Bioavailable ROCK2 Inhibitors
2个月前
已完结
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