Lv4
570 积分 2023-11-09 加入
Preclinical translational physiologically based pharmacokinetic modeling for predicting human pharmacokinetics of proteolysis targeting chimeras: Case studies of vepdegestrant (ARV-471) and bavdegalutamide (ARV-110)
16天前
已完结
Phase 1 Dose-Escalation Study of [ 225 Ac]Ac-PSMA I&T in Patients with Metastatic Castration-Resistant Prostate Cancer: An Analysis of Safety, Tolerability, and Dosimetry
1个月前
已完结
The pharmacokinetics and pharmacodynamics of monoclonal antibodies--mechanistic modeling applied to drug development
1个月前
已关闭
Trispecific antibodies take to the clinic
1个月前
已完结
On the coupling between a basic FcRn mechanism and target-mediated disposition of antibodies
1个月前
已完结
Duration of Vascular Endothelial Growth Factor Suppression After Intravitreal Injection of Brolucizumab and Aflibercept in Macaque Eyes
1个月前
已完结
POS0277 CANAKINUMAB PROPHYLAXIS WITHOUT CORTICOSTEROIDS, PREVENTED FLARES IN PATIENTS INITIATING PEGLOTICASE WITH METHOTREXATE FOR UNCONTROLLED GOUT: A PROSPECTIVE, MULTICENTER, OPEN LABEL, PROOF-OF-CONCEPT, PHASE IV, CLINICAL TRIAL
3个月前
已关闭
Nonlinear pharmacokinetics
4个月前
已关闭
Effects of Gastric Acid Suppression, Cytochrome P4503A Inhibition and Induction, and Food on the Pharmacokinetics of Tinlarebant in Healthy Adults
4个月前
已完结
Blood–brain barrier transporters: a translational consideration for CNS delivery of neurotherapeutics
6个月前
已完结
A comparative study of bone remodeling around hydroxyapatite-coated and novel radial functionally graded dental implants using finite element simulation
10个月前
已采纳
Fatigue Test Evaluation of a Customised Humeral Component for an instrumented Total Elbow Prosthesis and strain validation study
10个月前
已采纳
[89Zr]Zr-girentuximab PET-CT imaging to diagnose, characterize, and differentiate clear-cell renal cell carcinoma
10个月前
已采纳
Trends and sociodemographic patterns in hypertension prevalence and treatment in China
10个月前
已采纳
Safety and efficacy of apitegromab in nonambulatory type 2 or type 3 spinal muscular atrophy (SAPPHIRE): a phase 3, double-blind, randomised, placebo-controlled trial
10个月前
已采纳
Metastases-directed therapy in addition to standard systemic therapy in oligometastatic castration-resistant prostate cancer in Canada (GROUQ-PCS 9): a multicentre, open-label, randomised, phase 2 trial
10个月前
已采纳
Neoadjuvant trastuzumab, pertuzumab, and chemotherapy versus trastuzumab emtansine plus pertuzumab in patients with HER2-positive breast cancer (KRISTINE): a randomised, open-label, multicentre, phase 3 trial
10个月前
已采纳
Trifluridine/tipiracil versus placebo in patients with heavily pretreated metastatic gastric cancer (TAGS): a randomised, double-blind, placebo-controlled, phase 3 trial
10个月前
已采纳
TiO2/P(AM-co-AMPS) monolith prepared by CO2-in-water HIPEs and its potential application in wastewater treatment
10个月前
已采纳
Structure of full-length cobalamin-dependent methionine synthase and cofactor loading captured in crystallo
10个月前
已采纳
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