Lv6
2824 积分 2025-09-11 加入
Targeting ERK, an Achilles' Heel of the MAPK pathway, in cancer therapy
1个月前
已完结
RAS-targeted therapies: is the undruggable drugged?
1个月前
已完结
Regulated induced proximity targeting chimeras—RIPTACs—A heterobifunctional small molecule strategy for cancer selective therapies
1个月前
已完结
Discovery of potent small molecule PROTACs targeting mutant EGFR
1个月前
已完结
Design and synthesis of selective degraders of EGFRL858R/T790M mutant
1个月前
已完结
Engineered Monoclonal Antibody with Novel Antigen-Sweeping Activity In Vivo
1个月前
已完结
Antibody recycling by engineered pH-dependent antigen binding improves the duration of antigen neutralization
1个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
2个月前
已完结
Tilting the Scales toward EGFR Mutant Selectivity: Expanding the Scope of Bivalent “Type V” Kinase Inhibitors
2个月前
已完结
Overcoming EGFR(T790M) and EGFR(C797S) resistance with mutant-selective allosteric inhibitors
2个月前
已完结