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A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
5小时前
待确认
Abstract 3318: GFH375 (VS-7375): An oral, selective KRAS G12D (ON/OFF) inhibitor with potent anti-tumor efficacy
8天前
已关闭
A neomorphic protein interface catalyzes covalent inhibition of RAS G12D aspartic acid in tumors
8天前
已完结
Dual Inhibitors of KRASG12D and HSP90 are Effective Against KRASG12D Inhibitor Resistance
14天前
已完结
GCLM lactylation mediated by ACAT2 promotes ferroptosis resistance in KRASG12D-mutant cancer
14天前
已完结
AGER-dependent macropinocytosis drives resistance to KRAS-G12D–targeted therapy in advanced pancreatic cancer
14天前
已完结
The Ketogenic Diet Modulates Tumor-Associated Neutrophil Polarization via the AMOT-YAP/TAZ Axis to Inhibit Colorectal Cancer Progression
19天前
已完结
NINJ1: A new player in multiple sclerosis pathogenesis and potential therapeutic target
19天前
已完结
Hypoxia-Inducible Factor 1-Alpha (HIF-1α) and Cancer: Mechanisms of Tumor Hypoxia and Therapeutic Targeting
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已完结
Cuproptosis: A novel therapeutic target for overcoming cancer drug resistance
20天前
已完结
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