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88 积分 2025-03-02 加入
GSPT1 degraders: research progress, development strategies and challenges
25天前
已完结
A cereblon-based glue degrader of NEK7 regulates NLRP3 inflammasome in a context-dependent manner
1个月前
已关闭
Development of a Buchwald–Hartwig Amination for an Accelerated Library Synthesis of Cereblon Binders
5个月前
已完结
Studies of the selective O-alkylation and dealkylation of flavonoids. 10. Selective demethylation of 7-hydroxy-3,5,8-trimethoxyflavones with anhydrous aluminum halide in acetonitrile or ether
6个月前
已完结
Selective and Potent Molecular Glue Degraders for NIMA‐related Kinase 7
6个月前
已完结
A bioisosteric approach to the discovery of novel N-aryl-N′-[4-(aryloxy)cyclohexyl]squaramide-based activators of eukaryotic initiation factor 2 alpha (eIF2α) phosphorylation
6个月前
已完结
Discovery and Optimization of First-in-Class Molecular Glue Degraders of the WIZ Transcription Factor for Fetal Hemoglobin Induction to Treat Sickle Cell Disease
6个月前
已完结
Accelerating Effect Induced by the Structure of α-Amino Acid in the Copper-Catalyzed Coupling Reaction of Aryl Halides with α-Amino Acids. Synthesis of Benzolactam-V8
7个月前
已完结
Copper-catalyzed N-(hetero)arylation of amino acids in water
7个月前
已完结
Novel dibenzo[b,d]furan-1H-1,2,4-triazole derivatives: Synthesis and antitumor activity
7个月前
已完结