Lv7
4120 积分 2020-09-23 加入
Safety considerations for cereblon-recruiting targeted protein degraders
17天前
已完结
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
17天前
已完结
LGR4 cooperates with PrPc to endow the stemness of colorectal cancer stem cells contributing to tumorigenesis and liver metastasis
22天前
已完结
LGR4 cooperates with PrPc to endow the stemness of colorectal cancer stem cells contributing to tumorigenesis and liver metastasis
22天前
已完结
Targeted activation of ferroptosis in colorectal cancer via LGR4 targeting overcomes acquired drug resistance
22天前
已完结
Anti-tumor activity of camptothecin analog conjugate of an RSPO4-based peptibody targeting LGR4/5/6 in preclinical models of colorectal cancer
22天前
已完结
Design, synthesis and biological evaluation of 2-aminopyridine derivatives as USP7 inhibitors
23天前
已完结
The MEK–RAF molecular glue IK-595 has potent antitumor activity across RAS/MAPK pathway-altered cancers
1个月前
已完结
Characterization of an anti-STEAP1 T-cell dependent bispecific antibody for the treatment of prostate cancer and associated toxicity in cynomolgus monkeys
1个月前
已完结
Discovery and Optimization of a Potent, Efficacious, and Brain-Penetrant Inhibitor of KRAS G12C
1个月前
已完结
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