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20 积分 2021-11-18 加入
Quantitative systems toxicology: modelling to mechanistically understand and predict drug safety
1小时前
待确认
The state of the art in secondary pharmacology and its impact on the safety of new medicines
1小时前
已完结
Application of proteolysis targeting chimeric (PROTAC) technology in protein regulation and drug development
6天前
已完结
Novel Mechanisms of Resistance in CLL: Variant BTK Mutations in Second-Generation and Noncovalent BTK Inhibitors
6天前
已完结
Preclinical characterization of TGRX-678, a brain-penetrant allosteric inhibitor of BCR::ABL1
12天前
已完结
Molecular glue CELMoD compounds are regulators of cereblon conformation
6个月前
已完结
RLY-4008, the First Highly Selective FGFR2 Inhibitor with Activity across FGFR2 Alterations and Resistance Mutations
10个月前
已完结
Structural Feature Analyzation Strategies toward Discovery of Orally Bioavailable PROTACs of Bruton’s Tyrosine Kinase for the Treatment of Lymphoma
1年前
已完结
Discovery of Zanubrutinib (BGB-3111), a Novel, Potent, and Selective Covalent Inhibitor of Bruton’s Tyrosine Kinase
1年前
已完结
Nx-5948, a Selective Degrader of BTK with Activity in Preclinical Models of Hematologic and Brain Malignancies
1年前
已完结
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