Lv71
3510 积分 2022-07-29 加入
Activating mutations in the MET kinase domain co-occur with other driver oncogenes and mediate resistance to targeted therapy in NSCLC
9天前
已完结
Reversible Small Molecule Multivariant Ras Inhibitors Display Tunable Affinity for the Active and Inactive Forms of Ras
12天前
已完结
Switching It up with New KRAS Inhibitors
13天前
已完结
Rational Design, Synthesis, and Biological Evaluation of Novel c-Met Degraders for Lung Cancer Therapy
1个月前
已完结
Discovery of MAP855, an Efficacious and Selective MEK1/2 Inhibitor with an ATP-Competitive Mode of Action
1个月前
已完结
Design, Synthesis, and Biological Evaluation of 5-Amino-4-fluoro-1H-benzo[d]imidazole-6-carboxamide Derivatives as Novel and Potential MEK/RAF Complex Inhibitors Based on the “Clamp” Strategy
1个月前
已完结
Discovery of A-910, a Highly Potent and Orally Bioavailable Dual MerTK/Axl-Selective Tyrosine Kinase Inhibitor
1个月前
已完结
Discovery of Novel Macrocyclic MERTK/AXL Dual Inhibitors
1个月前
已完结
UNC9426, a Potent and Orally Bioavailable TYRO3-Specific Inhibitor
1个月前
已完结
Synthesis, activity, and their relationships of 2,4-diaminonicotinamide derivatives as EGFR inhibitors targeting C797S mutation
1个月前
已完结
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