Lv7
3490 积分 2021-01-31 加入
Targeting SMC3 deacetylation synergizes with XPO1 inhibition to reprogram the epigenetic landscape and suppress NPM1-mutated acute myeloid leukemia
6天前
已完结
A first-in-pediatric study of ALRN-6924, a novel stapled-peptide dual MDM2/MDMX inhibitor, for children with advanced hematologic and solid malignancies
19天前
已完结
The Care and Cure of the Leukemias in 2026
1个月前
已完结
Venetoclax and arsenic showed synergistic anti‐leukemia activity in vitro and in vivo for acute myeloid leukemia with the NPM1 mutation
1个月前
已完结
UBE2C promotes pancreatic tumorigenesis by KRAS stabilization via APC/CCDH1-mediated WDR76 degradation
1个月前
已完结
Morusin targets DNA methyltransferase 1 to trigger senescence and sensitizes colorectal cancer to senolytic therapy
1个月前
已完结
Genome-wide CRISPR/Cas9 screen identified MCL1 as a senolytic target for clearing palbociclib-induced senescent and PD-L1-positive cells in colorectal cancer
1个月前
已完结
A new approach for elimination of apoptotic resistance caused by MDM2/MDMX amplification in chronic lymphocytic leukemia: combination of ALRN-6924 and radiofrequency exposure
1个月前
已完结
Transposable elements shape stemness in normal and leukemic hematopoiesis
1个月前
已完结
Hematopoietic stem cell transplantation chemotherapy causes microglia senescence and peripheral macrophage engraftment in the brain
1个月前
已完结
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