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4060 积分 2021-01-24 加入
Atom-Economical and Scalable Asymmetric Synthesis of Daridorexant Key Starting Material ( S )-2-Methylproline via the Memory of Chirality
1个月前
已完结
A Second-Generation Route to the Cereblon Fragment of ARV-471, Vepdegestrant
2个月前
已完结
Route Development toward a Pyrazine Building Block to Enable Early Scale-Up Campaigns
2个月前
已完结
Solvent Entrapment of BI 763963 by Solid Solution Formation
2个月前
已完结
Continuous Reduction of an Ester to Aldehyde in CSTR: From Laboratory to Industrial Plant
4个月前
已完结
Development of a Manufacturing Process for a Key (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole Intermediate for Orforglipron. Part II. Development of a CSTR Process for Evans Auxiliary-Assisted Asymmetric 1,4-Addition
5个月前
已完结
Development of a Manufacturing Process for a Key (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole Intermediate for Orforglipron. Part III. Development of a Telescoped Phase-Transfer-Catalyzed Alkylation and Cyclopropanation Process
5个月前
已完结
Development of a Manufacturing Process for a Key (S)-5-(2,2-Dimethyltetrahydro-2H-pyran-4-yl)-1H-indole Intermediate for Orforglipron. Part I. Selection of an Evans Auxiliary-Assisted Asymmetric 1,4-Addition Route
5个月前
已完结
Strategy to Assess and Control Nitrosamine Formation in API during Storage: A Sitagliptin Case Study
5个月前
已完结
Potential for the Formation of N-Nitrosamines during the Manufacture of Active Pharmaceutical Ingredients: An Assessment of the Risk Posed by Trace Nitrite in Water
5个月前
已完结
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