Lv61
2270 积分 2021-06-21 加入
C–H Aminoalkylation of 5-Membered Heterocycles: Influence of Descriptors, Data Set Size, and Data Quality on the Predictiveness of Machine Learning Models and Expansion of the Substrate Space Beyond 1,3-Azoles
24天前
已完结
2-Phenylquinazolin-4(3H)-one, a class of potent PDE5 inhibitors with high selectivity versus PDE6
26天前
已完结
Discovery of ARD-2051 as a Potent and Orally Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of Androgen Receptor for the Treatment of Advanced Prostate Cancer
26天前
已完结
Discovery of 2-(Pyrazol-4-yl)-quinazolin-4(3H)-one Derivatives as Subnanomolar BRD4 BD2 Inhibitors with High Selectivity via a Bioisosterism Approach
27天前
已完结
A novel cereblon modulator for targeted protein degradation
1个月前
已完结
Exploiting Ancillary Ligation To Enable Nickel-Catalyzed C–O Cross-Couplings of Aryl Electrophiles with Aliphatic Alcohols
1个月前
已完结
A Comparative Ancillary Ligand Survey in Palladium‐Catalyzed C–O Cross‐Coupling of Primary and Secondary Aliphatic Alcohols
1个月前
已完结
Use of Tunable Ligands Allows for Intermolecular Pd-Catalyzed C−O Bond Formation
1个月前
已完结
Synthesis of tertiary alkyl amines via photoinduced copper-catalysed nucleophilic substitution
1个月前
已完结
Discovery of Highly Selective PARP7 Inhibitors with a Novel Scaffold for Cancer Immunotherapy
3个月前
已完结
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