Lv1
10 积分 2022-10-26 加入
Targeting Lysophosphatidic Acid Receptor 1 (LPAR1) with siRNA-Lipid Nanoparticles (siRNA-LNP) Is a Potential Therapeutic Approach for CKD -Associated Kidney Fibrosis
1天前
求助中
Bronchopulmonary dysplasia demonstrates dysregulated autotaxin/lysophosphatidic acid signaling in a neonatal mouse model
5天前
已完结
Discovery of an Oxycyclohexyl Acid Lysophosphatidic Acid Receptor 1 (LPA1) Antagonist BMS-986278 for the Treatment of Pulmonary Fibrotic Diseases
5天前
已完结
Integrin αEβ7: Molecular Features and Functional Significance in the Immune System
11天前
已完结
Integrin αEβ7: Molecular Features and Functional Significance in the Immune System
11天前
已完结
Discovery of Clinical Candidate 4-[2-(5-Amino-1H-pyrazol-4-yl)-4-chlorophenoxy]-5-chloro-2-fluoro-N-1,3-thiazol-4-ylbenzenesulfonamide (PF-05089771): Design and Optimization of Diaryl Ether Aryl Sulfonamides as Selective Inhibitors of NaV1.7
15天前
已完结
Bifunctional Compounds as Molecular Degraders for Integrin-Facilitated Targeted Protein Degradation
17天前
已完结
Internalization of the vedolizumab/α4β7 complex and kinetics of restoring functional activity
1个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
2个月前
已完结
Lessons learned in linking PROTACs from discovery to the clinic
5个月前
已完结
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