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12 积分 2025-07-17 加入
Macrocyclic Peptides as Drug Candidates: Recent Progress and Remaining Challenges
5天前
已完结
Crystal Structure and Immunoglobulin G Binding Properties of the Human Major Histocompatibility Complex-Related Fc Receptor,
10天前
已完结
DNA-Encoded Macrocyclic Peptide Libraries Enable the Discovery of a Neutral MDM2–p53 Inhibitor
12天前
已完结
Structural and molecular characterization of a small-molecule TNF-α–TNFR1 inhibitor modulating cell death signaling
14天前
已完结
Identification of an Orally Bioavailable Quinoline-Based Small-Molecule Tumor Necrosis Factor α (TNF-α) Inhibitor Featuring a Spirocyclic Scaffold
14天前
已完结
Ansamer‐Controlled Bicyclic Peptides as Integrin αvβ6 Targeting Agents
18天前
已完结
Generation of tumour‐necrosis‐factor‐α‐specific affibody1 molecules capable of blocking receptor binding in vitro
19天前
已完结
Discovery of an Anti-TNF-α 9-mer Peptide from a T7 Phage Display Library for the Treatment of Inflammatory Bowel Disease
19天前
已完结
Discovery of Zilucoplan: A Complement C5 Inhibitor for Treatment of Anti-Acetylcholine Receptor (AChR) Antibody-Positive Generalized Myasthenia Gravis (gMG)
25天前
已完结
Zilucoplan, a macrocyclic peptide inhibitor of human complement component 5, uses a dual mode of action to prevent terminal complement pathway activation
25天前
已完结
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