Lv51
880 积分 2023-06-01 加入
Molecular Degraders: A Comprehensive Review of Small Molecule Induced Protein Degradation Strategies
10天前
已完结
Generative AI-Assisted Discovery of HPK1 Inhibitors
13天前
已完结
Recent advances in c-Met-based dual inhibitors in the treatment of cancers
17天前
已完结
Discovery of ZSL-M028: A Potent, Selective and Orally Available Quinazoline-Based PLK4 Inhibitor Targeting TRIM37 -Amplified Neuroblastoma
18天前
已完结
Kilo-Scale-Enabled Route toward PF-07907063, a Type II Brain Penetrant cMET Inhibitor
22天前
已完结
Discovery of Pyrazolopyrazines as Selective, Potent, and Mutant-Active MET Inhibitors with Intracranial Efficacy
22天前
已完结
Discovery of KIN-8741, a Highly Selective Type IIb c-Met Kinase Inhibitor with Broad Mutation Coverage and Quality Drug-Like Properties for the Treatment of Cancer
26天前
已完结
Research Progress in Targeting GSPT1: Molecular Glues, Bifunctional Degraders, and Antibody-Enabled Molecular Glues for Cancer Therapy
1个月前
已完结
Beyond Target Occupancy in Triple-Negative Breast Cancer: A Medicinal Chemistry Perspective on Modality-Guided Design for Durable Network Control
1个月前
已完结
Routes to molecular glue degrader discovery
1个月前
已完结