Lv5
820 积分 2023-06-01 加入
Routes to molecular glue degrader discovery
12小时前
已完结
Induced proximity-based therapeutic modalities
1个月前
已完结
Molecular glues evolve from serendipity to rational design
1个月前
已完结
Complete Accounts of Integrated Drug Discovery and Development: Recent Examples from the Pharmaceutical Industry Volume 5
4个月前
已完结
TDP-43 Modulation by Tau-Tubulin Kinase 1 Inhibitors: A New Avenue for Future Amyotrophic Lateral Sclerosis Therapy
4个月前
已完结
Discovery of Potent and Brain-Penetrant Tau Tubulin Kinase 1 (TTBK1) Inhibitors that Lower Tau Phosphorylation In Vivo
4个月前
已完结
Efficient synthesis of tert-butyl 3-cyano-3-cyclopropyl-2-oxopyrrolidine-4-carboxylates: Highly functionalized 2-pyrrolidinone enabling access to novel macrocyclic Tyk2 inhibitors
5个月前
已完结
Design, Synthesis, and Biological Evaluation of Macrocyclic 2-Amino-4-phenylaminopyrimidine Derivatives as Potent JAK2 Inhibitors
5个月前
已完结
argeting MET: Discovery of Small Molecule Inhibitors as Non-Small Cell Lung Cancer Therapy
5个月前
已完结
Structure-Based Optimization of the Third Generation Type II Macrocycle TRK Inhibitors with Improved Activity against Solvent-Front, xDFG, and Gatekeeper Mutations
5个月前
已完结