Lv1
76 积分 2025-02-24 加入
PSMA-Guided PROTAC Degraders for Tumor-Specific Protein Degradation in Prostate Cancer
1个月前
已完结
New Reversible Covalent Warheads: Cyanobenzothiazoles Recruiting DCAF16 for Targeted Protein Degradation
2个月前
已完结
Diaryl Ureas as an Antiprotozoal Chemotype
3个月前
已完结
DCAF16-Based Covalent Handle for the Rational Design of Monovalent Degraders
3个月前
已完结
Discovery of Chromone Derivatives as Selective BLT1 Inhibitors for Alleviating Acute Lung Injury and Sepsis
3个月前
已完结
Hepatoprotective effects of the dual peroxisome proliferator-activated receptor alpha/delta agonist, GFT505, in rodent models of nonalcoholic fatty liver disease/nonalcoholic steatohepatitis
4个月前
已完结
Discovery of the First Subnanomolar PPARα/δ Dual Agonist for the Treatment of Cholestatic Liver Diseases
4个月前
已完结
Design, Synthesis, and Biological Evaluation of Triazolone Derivatives as Potent PPARα/δ Dual Agonists for the Treatment of Nonalcoholic Steatohepatitis
4个月前
已完结
Discovery of 1,2,3,4-Tetrahydrochromeno[3,4c]pyridin-5-one Derivatives as Novel MTHFD Inhibitors for the Treatment of Acute Myeloid Leukemia
5个月前
已完结
Discovery of DN1679 as a Potent, Orally Bioavailable, and Highly Selective CDK12/13 Dual Degrader for the Treatment of Triple-Negative Breast Cancer
7个月前
已完结
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