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18 积分 2025-03-05 加入
The Molecular Biology of Phosphodiesterase 4 Enzymes as Pharmacological Targets: An Interplay of Isoforms, Conformational States, and Inhibitors
9小时前
已完结
Beyond PDE4 inhibition: A comprehensive review on downstream cAMP signaling in the central nervous system
5天前
已完结
Amyloid-β-driven glymphatic dysfunction in Alzheimer’s disease model mice is driven by Ca2+-mediated increases in astrocytic cholesterol
5天前
已完结
RETRACTED: Injection of exogenous amyloid-β oligomers aggravated cognitive deficits, and activated necroptosis, in APP23 transgenic mice
1个月前
已完结
Aminoalkyl Derivatives of 8‐Alkoxypurine‐2,6‐diones: Multifunctional 5‐HT1A/5‐HT7 Receptor Ligands and PDE Inhibitors with Antidepressant Activity
2个月前
已完结
A Yeast-Based Chemical Screen Identifies a PDE Inhibitor That Elevates Steroidogenesis in Mouse Leydig Cells via PDE8 and PDE4 Inhibition
2个月前
已完结
Role of phosphodiesterases in the shaping of sub-plasma membrane cAMP oscillations and pulsatile insulin secretion
4个月前
已完结
The High-Affinity cAMP-Specific Phosphodiesterase 8B Controls Steroidogenesis in the Mouse Adrenal Gland
4个月前
已完结
Effects of phosphodiesterase 7 inhibition by RNA interference on the gene expression and differentiation of human mesenchymal stem cell-derived osteoblasts
4个月前
已完结
1,5-Substituted nipecotic amides: Selective PDE8 inhibitors displaying diastereomer-dependent microsomal stability
4个月前
已完结
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