Lv41
656 积分 2024-04-10 加入
Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function
9小时前
求助中
Peripheral blood biomarkers RCAN1, Clusterin, RAGE, and malondialdehyde for early diagnosis and progression of Alzheimer’s disease
7天前
已完结
LRRK2 and GBA1 in Lewy body diseases: neuropathological subtypes at opposite ends of a spectrum?
7天前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
28天前
已完结
Dysregulation of astrocytic DNAJC6 contributes to sporadic Parkinson’s disease pathogenesis
28天前
已完结
Lack of Cerebrospinal Fluid α‐Synuclein Seeding in VPS35 D620N‐ and LRRK2 Y1699C‐Linked Parkinson's Disease
1个月前
已完结
Self-Assembling Peptide Nanotherapeutics: Precision Targeting for Acute Lung Injury and Multimodal Intervention in Chronic Pulmonary Fibrosis
1个月前
已完结
LRRK2-targeting antisense oligonucleotide in Parkinson’s disease: a phase 1 randomized controlled trial
1个月前
已完结
LRRK2-targeting antisense oligonucleotide in Parkinson’s disease: a phase 1 randomized controlled trial
1个月前
已完结
Cytokine associated neuroinflammation in Parkinson’s disease: Molecular pathways, therapeutic targets, and translational insights
1个月前
已关闭
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