Lv4
616 积分 2024-04-10 加入
Knockout of the LRRK2-counteracting RAB phosphatase PPM1H disrupts axonal autophagy and exacerbates alpha-synuclein aggregation
2小时前
待确认
MMP7-Triggered mitophagy by regulating parkin-mediated ubiquitination of VDAC1 confers anoikis resistance in the epithelium of hyperplastic prostate
27天前
已完结
How endosomal PIKfyve inhibition prevents viral membrane fusion and entry
1个月前
已完结
PIKfyve preserves endolysosomal function in photoreceptors and RPE cells to maintain retinal integrity
1个月前
已完结
Lung microbiota-derived deoxyinosine alleviates TBI-aggravated sepsis-induced lung injury via the S100A9/RAGE pathway
1个月前
已完结
Preformed fibrils of α-synuclein rapidly activate LRRK2 on early endosomes, driving Rab5 phosphorylation and disrupting endolysosomal and synaptic function
1个月前
已完结
Peripheral blood biomarkers RCAN1, Clusterin, RAGE, and malondialdehyde for early diagnosis and progression of Alzheimer’s disease
1个月前
已完结
LRRK2 and GBA1 in Lewy body diseases: neuropathological subtypes at opposite ends of a spectrum?
1个月前
已完结
Discovery of Potent, Selective, CNS-Penetrant Macrocyclic LRRK2 Inhibitors for the Treatment of Parkinson’s Disease
2个月前
已完结
Dysregulation of astrocytic DNAJC6 contributes to sporadic Parkinson’s disease pathogenesis
2个月前
已完结
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