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1880 积分 2023-10-19 加入
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Development and qualification of an in vitro assay to determine target mediated internalization of TREM2 receptor specific antibodies for TMDD assessment
1天前
已完结
Microglial MHC-I induction with aging and Alzheimer’s is conserved in mouse models and humans
14天前
已完结
Loss of PILRA promotes microglial immunometabolism to reduce amyloid pathology in cell and mouse models of Alzheimer’s disease
15天前
已完结
Bispecific and multispecific antibodies in oncology: opportunities and challenges
20天前
已完结
Microglia contributes to plaque growth by cell death due to uptake of amyloid β in the brain of Alzheimer's disease mouse model
20天前
已完结
Decoding of the Role of TREM2 in Neuropathic Pain: Molecular Pathway and Neuroinflammatory Mechanism
23天前
已完结
Therapeutic targeting of neuroimmune mechanisms in neurodegeneration
27天前
已完结
A tetravalent TREM2 agonistic antibody reduced amyloid pathology in a mouse model of Alzheimer’s disease
28天前
已完结
AD-linked R47H-TREM2mutation induces disease-enhancing microglial states via AKT hyperactivation
29天前
已完结
TREM2 activation by first-in-class direct small molecule agonists: DEL screening, optimization, biophysical validation, and functional characterization
29天前
已完结
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