Lv44
498 积分 2025-09-04 加入
Structural Mass Spectrometry Probes the Inhibitor-Induced Allosteric Activation of CDK12/CDK13-Cyclin K Dissociation
1小时前
待确认
Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1)
3小时前
待确认
Discovery of Small-Molecule Degraders of the CDK9-Cyclin T1 Complex for Targeting Transcriptional Addiction in Prostate Cancer
4小时前
待确认
Harnessing the Magic Methyl Effect: Discovery of CLPP-2068 as a Novel HsClpP Activator for the Treatment of Diffuse Large B-Cell Lymphoma
3天前
已完结
Diterpenoids and diarylheptanoids from the fruits of Alpinia zerumbet and their anti-inflammatory activity
3天前
已完结
Purification, structural characterization, and anti-ulcerative colitis activity of a novel pectin-like polysaccharide AH-H4–1 from Alhagi honey
7天前
已完结
Augmentation of PRDX1–DOK3 interaction alleviates rheumatoid arthritis progression by suppressing plasma cell differentiation
15天前
已完结
Rapid Discovery of Celastrol Derivatives as Potent and Selective PRDX1 Inhibitors via Microplate-Based Parallel Compound Library and In Situ Screening
15天前
已完结
Fluorescence-Coupled Ubiquitination Assay as a High-Throughput Screening Strategy for Novel Cereblon Degraders
15天前
已完结
Discovery of Novel Imidazo[1,2-B]Pyridazine Derivatives as Potent Covalent Inhibitors of Cdk12/13
15天前
已完结