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130 积分 2025-02-02 加入
Tu1727 MRT-6160, A VAV1-DIRECTED MOLECULAR GLUE DEGRADER, INHIBITS DISEASE PROGRESSION IN A T-CELL TRANSFER MEDIATED MURINE COLITIS MODEL CONCOMITANT WITH REDUCED CALPROTECTIN EXPRESSION
2个月前
已完结
P164 MRT-6160, a VAV1-directed molecular glue degrader, inhibits disease progression and inflammation in a T-cell transfer model of Colitis
2个月前
已完结
Development of PROTACs Targeting the Moonlighting Enzyme Nicotinamide Phosphoribosyltransferase (NAMPT) for Breast Cancer Therapy
2个月前
已完结
Sirt5 in mediating endothelial and vascular dysfunction: a novel target in aging-related vascular diseases
2个月前
已完结
SIRT5 slows skeletal muscle ageing by alleviating inflammation
3个月前
已完结
SIRT5 safeguards against primate skeletal muscle ageing via desuccinylation of TBK1
3个月前
已完结
Sirt5 in mediating endothelial and vascular dysfunction: a novel target in aging-related vascular diseases
3个月前
已完结
Mitochondrial Sirtuins in Cancer: A Revisited Review from Molecular Mechanisms to Therapeutic Strategies
3个月前
已完结
Mitochondrial Protease Targeting Chimeras for Mitochondrial Matrix Protein Degradation
3个月前
已完结
Mechanism-Based Inhibitors of the Human Sirtuin 5 Deacylase: Structure-Activity Relationship, Biostructural, and Kinetic Insight
3个月前
已完结