Lv1
46 积分 2025-02-02 加入
β-Lactones as Specific Inhibitors of ClpP Attenuate the Production of Extracellular Virulence Factors of Staphylococcus aureus
1个月前
已完结
Hijacking Extracellular Targeted Protein Degrader–Drug Conjugates for Enhanced Drug Delivery
1个月前
已完结
Abstract LB049: DAC-002, a novel IKZF1/3 MGD-CD38 degrader-antibody conjugate for MM treatment
1个月前
已完结
Targeted degrader conjugates (TDCs): Modalities for precision delivery of PROTACs and molecular glue degraders
1个月前
已完结
Discovery of first-in-class calr-targeted precision ADCs delivering a CDK9degrader payload for the treatment of calr-mutated MPNs
1个月前
已关闭
Targeted degradation of c-Myc through the midnolin–proteasome pathway
1个月前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
1个月前
已完结
X-ray Crystallography-Guided Discovery of a Potent Dual-Pocket Competitive SIRT5 Inhibitor against Sepsis-Associated AKI
3个月前
已完结
Structure–Activity Relationship Studies of 2,4,5-Trisubstituted Pyrimidine Derivatives Leading to the Identification of a Novel and Potent Sirtuin 5 Inhibitor against Sepsis-Associated Acute Kidney Injury
3个月前
已完结
Tu1727 MRT-6160, A VAV1-DIRECTED MOLECULAR GLUE DEGRADER, INHIBITS DISEASE PROGRESSION IN A T-CELL TRANSFER MEDIATED MURINE COLITIS MODEL CONCOMITANT WITH REDUCED CALPROTECTIN EXPRESSION
7个月前
已完结
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