Lv5
1080 积分 2023-03-07 加入
Discovery of SMD-3236: A Potent, Highly Selective and Efficacious SMARCA2 Degrader for the Treatment of SMARC4-Deficient Human Cancers
10天前
已完结
Discovery of Novel, Potent, and Orally Bioavailable SMARCA2 Proteolysis-Targeting Chimeras with Synergistic Antitumor Activity in Combination with Kirsten Rat Sarcoma Viral Oncogene Homologue G12C Inhibitors
10天前
已完结
Discovery of FHD-286, a First-in-Class, Orally Bioavailable, Allosteric Dual Inhibitor of the Brahma Homologue (BRM) and Brahma-Related Gene 1 (BRG1) ATPase Activity for the Treatment of SWItch/Sucrose Non-Fermentable (SWI/SNF) Dependent Cancers
10天前
已完结
SMARCA2 protein: Structure, function and perspectives of drug design
10天前
已完结
ByeTAC: Bypassing E-Ligase-Targeting Chimeras for Direct Proteasome Degradation
16天前
已完结
Acyl-CoA Synthetase Long-Chain Isoenzymes in Kidney Diseases: Mechanistic Insights and Therapeutic Implications
1个月前
已完结
Low acyl-CoA synthetase 5 expression in colorectal carcinomas is prognostic for early tumour recurrence
1个月前
已完结
ACSL family: The regulatory mechanisms and therapeutic implications in cancer
1个月前
已完结
ACSL5 promotes lipid deposition and lipoapoptosis in proximal tubular epithelial cells of diabetic kidney disease
1个月前
已完结
A highly sensitive and specific Homo1-based real-time qPCR method for quantification of human umbilical cord mesenchymal stem cells in rats
1个月前
已完结
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