Lv1
70 积分 2025-07-08 加入
Design of Potent and Selective BCL6 Transcriptional Chemical Inducers of Proximity through Linker Optimization
1个月前
已完结
Reporter Gene Assay for Monitoring BCL6 Reactivation
2个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation
5个月前
已完结
Discovery of Potent and Highly Selective Interleukin-2-Inducible T-Cell Kinase Degraders with In Vivo Activity
5个月前
已完结
Discovery of highly potent and selective CRBN-recruiting EGFRL858R/T790M degraders in vivo
5个月前
已完结
NEK7 phosphorylation amplifies NLRP3 inflammasome activation downstream of potassium efflux and gasdermin D
6个月前
已完结
Addressing Kinase-Independent Functions of Fak via PROTAC-Mediated Degradation
7个月前
已完结
Highly Selective PTK2 Proteolysis Targeting Chimeras to Probe Focal Adhesion Kinase Scaffolding Functions
8个月前
已完结
Cryo-EM structures of GPR75 reveal an occluded orthosteric pocket challenging conventional drug discovery paradigms for an anti-obesity target
8个月前
已完结
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
8个月前
已完结
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