Lv31
230 积分 2025-07-15 加入
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
1小时前
已完结
DNA repair dysregulation from cancer driver to therapeutic target
4小时前
已完结
PARP inhibitors: Synthetic lethality in the clinic
5小时前
已完结
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
27天前
已完结
An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing
27天前
已完结
Evaluation of siRNA Stability and Interaction with Serum Components Using an Agarose Gel-Based Single-Molecule FRET Labeling Method
1个月前
已完结
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
3个月前
已完结
A dual-luciferase reporter system for characterization of small RNA target genes in both mammalian and insect cells
4个月前
已完结
FOXP2/SOS1/AKT negative feedback loop inhibits cell proliferation in KRAS-mutant colorectal cancer
4个月前
已完结
Inhibition of CXCL10 and IFN-γ ameliorates myocarditis in preclinical models of SARS-CoV-2 mRNA vaccination
5个月前
已完结
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