Lv2
190 积分 2025-07-15 加入
Bis(morpholino-1,3,5-triazine) derivatives: potent adenosine 5'-triphosphate competitive phosphatidylinositol-3-kinase/mammalian target of rapamycin inhibitors: discovery of compound 26 (PKI-587), a highly efficacious dual inhibitor
1个月前
已完结
A directly labeled TR-FRET assay for monitoring phosphoinositide-3-kinase activity
1个月前
已完结
Two decades of PARP inhibitor synthetic lethality in cancer
2个月前
已完结
ATM and ATR Substrate Analysis Reveals Extensive Protein Networks Responsive to DNA Damage
2个月前
已完结
The DNA Damage Response: Ten Years After
2个月前
已完结
Discovery of 6-Fluoro-5-{4-[(5-fluoro-2-methyl-3-oxo-3,4-dihydroquinoxalin-6-yl)methyl]piperazin-1-yl}-N-methylpyridine-2-carboxamide (AZD9574): A CNS-Penetrant, PARP1-Selective Inhibitor
2个月前
已完结
DNA repair dysregulation from cancer driver to therapeutic target
2个月前
已完结
PARP inhibitors: Synthetic lethality in the clinic
2个月前
已完结
Mechanisms and optimization of in vivo delivery of lipophilic siRNAs
3个月前
已完结
An albumin-mediated cholesterol design-based strategy for tuning siRNA pharmacokinetics and gene silencing
3个月前
已完结
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