Lv21
188 积分 2025-08-18 加入
Human GLP-1 receptor transmembrane domain structure in complex with allosteric modulators
2小时前
待确认
Bicyclic Heterocyclic Replacement of an Aryl Amide Leading to Potent and Kinase-Selective Adaptor Protein 2-Associated Kinase 1 Inhibitors
27天前
已完结
Development and therapeutic potential of adaptor-associated kinase 1 inhibitors in human multifaceted diseases
27天前
已完结
Discovery, Structure–Activity Relationships, and In Vivo Evaluation of Novel Aryl Amides as Brain Penetrant Adaptor Protein 2-Associated Kinase 1 (AAK1) Inhibitors for the Treatment of Neuropathic Pain
27天前
已完结
Bioisosteres of the Phenyl Ring: Recent Strategic Applications in Lead Optimization and Drug Design
1个月前
已完结
Rab29-dependent asymmetrical activation of leucine-rich repeat kinase 2
1个月前
已完结
Discovery of Elironrasib (RMC-6291), a Potent and Orally Bioavailable, RAS(ON) G12C-Selective, Covalent Tricomplex Inhibitor for the Treatment of Patients with RAS G12C-Addicted Cancers
1个月前
已完结
Rh-Catalyzed [8+1] Cycloaddition of Vinyl Biscyclopropanes with CO for the Synthesis of Nine-Membered Carbocycles
1个月前
已完结
Biomni: A General-Purpose Biomedical AI Agent
2个月前
已关闭
The structure of the ARE-binding domains of Hu antigen R (HuR) undergoes conformational changes during RNA binding
2个月前
已完结