Lv6
3020 积分 2025-12-02 加入
Discovery of Highly Potent and Efficient CBP/p300 Degraders with Strong In Vivo Antitumor Activity
8天前
已完结
Discovery of Novel CBP/p300 and BRD4 Dual-Target PROTACs with Potent Antitumor Activity in Prostate Cancer
8天前
已完结
Discovery of Cdc20/Hsp90 Dual-Target Inhibitors with Potent Antitumor Activity for Therapy of Acquired Resistant Melanoma
8天前
已完结
Integration of proteomic aging clocks in a phase 2a clinical trial supports simultaneous geroprotective assessment
14天前
已完结
Antibody-Mediated Delivery of Chimeric BRD4 Degraders. Part 2: Improvement of In Vitro Antiproliferation Activity and In Vivo Antitumor Efficacy
21天前
已完结
Bicyclic Isosteres of Pyridine/Piperidine: From Synthesis to Applications
22天前
已完结
Design, synthesis, and biological evaluation of novel pyrazolo [3,4-d]pyrimidine derivatives as potent PLK4 inhibitors for the treatment of TRIM37-amplified breast cancer
22天前
已完结
Research Progress in Targeting GSPT1: Molecular Glues, Bifunctional Degraders, and Antibody-Enabled Molecular Glues for Cancer Therapy
22天前
已完结
Discovery of 2,5-diaminopyrimidine derivatives as the first series of selective monomeric degraders of B-lymphoid tyrosine kinase
28天前
已完结
Generative design of novel bacteriophages with genome language models
1个月前
已完结