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40 积分 2025-05-26 加入
2-Aminopyridines as Potent and Selective Nav1.8 Inhibitors Exhibiting Efficacy in a Nonhuman Primate Pain Model
18天前
已完结
Tetra-acetylethylene : a new intermediate for synthesising heterocyclic rings
1个月前
已完结
In Vitro P-glycoprotein Efflux Ratio Can Predict the In Vivo Brain Penetration Regardless of Biopharmaceutics Drug Disposition Classification System Class
1个月前
已完结
Pharmacologic Characterization of LTGO-33, a Selective Small Molecule Inhibitor of the Voltage-Gated Sodium Channel NaV1.8 with a Unique Mechanism of Action
1个月前
已完结
Synthesis and Functionalization of New Tropanes Designed for Use as Scaffolds in Combinatorial Chemistry
2个月前
已完结
Efficient Synthesis of the Key Intermediate of Scopolamine by [4+3] Cycloaddition Reaction
2个月前
已完结
A convenient synthetic route to enantiopure N-tosylazetidines from α-amino acids
4个月前
已完结
Palladium‐Catalyzed Regioselective and Stereospecific Ring‐Opening Suzuki‐Miyaura Arylative Cross‐Coupling of 2‐Arylazetidines with Arylboronic Acids
4个月前
已完结
Syntheses of Chiral β- and γ-Amino Ethers, Morpholines, and Their Homologues via Nucleophilic Ring-Opening of Chiral Activated Aziridines and Azetidines
4个月前
已完结
Discovery of a Small Molecule TREM2 Agonist with Improved In Vitro Pharmacokinetic Profile and Validated Target Engagement
4个月前
已完结
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