Lv1
20 积分 2023-10-10 加入
Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor
16小时前
待确认
Homogeneous multi-payload antibody–drug conjugates
3个月前
已完结
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]
3个月前
已完结
Cyclic Peptide Linker Design and Optimization by Molecular Dynamics Simulations
3个月前
已完结
Incorporation of Three Extracyclic Arginine Residues into a Melanocortin Macrocyclic Agonist (c[Pro-His-DPhe-Arg-Trp-Dap-Lys(Arg-Arg-Arg-Ac)-DPro]) Decreases Food Intake When Administered Intrathecally or Subcutaneously Compared to a Macrocyclic Ligand Lacking Extracyclic Arginine Residues (c[Pro-His-DPhe-Arg-Trp-Dap-Ala-DPro)]
3个月前
已完结
Functional Characterization of Melanocortin-3 Receptor Variants Identify a Loss-of-Function Mutation Involving an Amino Acid Critical for G Protein-Coupled Receptor Activation
3个月前
已完结
A Novel Melanocortin 3 Receptor Gene (MC3R) Mutation Associated with Severe Obesity
3个月前
已关闭
Discovery of the Potent and Selective MC4R Antagonist PF-07258669 for the Potential Treatment of Appetite Loss
3个月前
已完结
Structural insight into selectivity of amylin and calcitonin receptor agonists
4个月前
已完结
The antibody–drug conjugate landscape
4个月前
已完结
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