Lv2
114 积分 2024-01-03 加入
Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy
2个月前
已完结
MTAP Deletion in Oncogenesis: A Synthetic Lethality Scenario
3个月前
已完结
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy
4个月前
已完结
Development of a Series of Pyrrolopyridone MAT2A Inhibitors
4个月前
已完结
Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening
4个月前
已完结
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads
4个月前
已完结
Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 Å Resolution
4个月前
已完结
Crystal structure of MAT2a with triazinone fragment 1 bound in the allosteric site
4个月前
已关闭
Crystal structures of human MATα2 (MAT2A) reveal the catalytic mechanism of S-adenosylmethionine synthesis. Structure,
4个月前
已关闭
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