Lv2
114 积分 2024-01-03 加入
Small-molecule PTPN2 Inhibitors Sensitize Resistant Melanoma to Anti-PD-1 Immunotherapy
5个月前
已完结
MTAP Deletion in Oncogenesis: A Synthetic Lethality Scenario
6个月前
已完结
Structure-Based Design and Optimization of Methionine Adenosyltransferase 2A (MAT2A) Inhibitors with High Selectivity, Brain Penetration, and In Vivo Efficacy
7个月前
已完结
Development of a Series of Pyrrolopyridone MAT2A Inhibitors
7个月前
已完结
Discovery of novel methionine adenosyltransferase 2A (MAT2A) allosteric inhibitors by structure-based virtual screening
7个月前
已完结
Leveraging Structure-Based Drug Design to Identify Next-Generation MAT2A Inhibitors, Including Brain-Penetrant and Peripherally Efficacious Leads
7个月前
已完结
Mechanism of Triphosphate Hydrolysis by Human MAT2A at 1.07 Å Resolution
7个月前
已完结
Crystal structure of MAT2a with triazinone fragment 1 bound in the allosteric site
7个月前
已关闭
Crystal structures of human MATα2 (MAT2A) reveal the catalytic mechanism of S-adenosylmethionine synthesis. Structure,
7个月前
已关闭
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