Lv5
1206 积分 2024-07-11 加入
Lessons learned in linking PROTACs from discovery to the clinic
5天前
已完结
Discovery of Potent and Selective Pyrrolo[2,3-d]pyrimidine Derivatives as Fourth-Generation EGFR Inhibitors Targeting Triple Mutations
13天前
已完结
Conformational Constrained 4-(1-Sulfonyl-3-indol)yl-2-phenylaminopyrimidine Derivatives as New Fourth-Generation Epidermal Growth Factor Receptor Inhibitors Targeting T790M/C797S Mutations
13天前
已完结
Discovery of Brigatinib (AP26113), a Phosphine Oxide-Containing, Potent, Orally Active Inhibitor of Anaplastic Lymphoma Kinase
17天前
已完结
Discovery of 3-[2-(Imidazo[1,2-b]pyridazin-3-yl)ethynyl]-4-methyl-N-{4-[(4-methylpiperazin-1-yl)methyl]-3-(trifluoromethyl)phenyl}benzamide (AP24534), a Potent, Orally Active Pan-Inhibitor of Breakpoint Cluster Region-Abelson (BCR-ABL) Kinase Including the T315I Gatekeeper Mutant
17天前
已完结
Early Process Development of a Heterobifunctional Protein Degrader
21天前
已完结
Synthesis of novel water soluble benzylazolium prodrugs of lipophilic azole antifungals
1个月前
已完结
Design, synthesis and antifungal activity of a novel water soluble prodrug of antifungal triazole
1个月前
已完结
Review of the Patent and Journal Literature: Synthesis and Final Forms of Antifungal Prodrug Isavuconazonium Sulfate
1个月前
已完结
Sulfenamides as prodrugs of NH-acidic compounds: A new prodrug option for the amide bond
1个月前
已完结