Lv5
1090 积分 2021-08-12 加入
Degron-independent recruitment of KAT2A expands the target space of CRBN molecular glues
2天前
已完结
Ifebemtinib plus garsorasib as first-line treatment for KRASG12C-mutated non-small-cell lung cancer in China: a multicentre, single-arm expansion cohort from a phase 1b/2 trial
3天前
已完结
Loss of the kinases TBK1 and IKKε sensitizes target cancer cells to T cell killing through an IFN-γ–mediated inflammatory death program
4天前
已完结
EML4-ALK mediates resistance to KRAS G12C inhibition and induces an oncogenic dependency by rewiring signaling through the wild-type RAS pathway
5天前
已完结
CAR T cell therapy selectively depletes disease-driving mutant calreticulin cells in xenotransplants and human organoid models of myelofibrosis
10天前
已完结
Actin cytoskeletal dynamics in hepatic myofibroblasts and fibrosis
12天前
已完结
Ubiquitin-like proteins NEDD8 and SUMO2 control epithelial homeostasis, regeneration, and inflammation
16天前
已完结
Adaptive feedback signaling via the FAK/SRC pathway promotes KRAS G12C inhibitor resistance
17天前
已关闭
PTK2/FAK inhibition triggers TMED9-mediated protective autophagy in pancreatic cancer cell via enhancing ERGIC-ERES contact
20天前
已完结
Cyclin-dependent kinase CDK1 targets cell-cell junction components and governs epithelial monolayer integrity throughout the cell cycle
25天前
已完结
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