Lv3
324 积分 2025-01-10 加入
Age-Dependent Changes in Mitochondrial Regulatory Mechanisms in the Spinal Cord of SOD1-G93A-Transgenic Mice with the Phenotype of Amyotrophic Lateral Sclerosis
1小时前
待确认
Discovery of a novel TFEB activator targeting lysosomal dysfunction in amyotrophic lateral sclerosis using artificial intelligence-based virtual screening
4个月前
已完结
REEP1 Preserves Motor Function in SOD1G93A Mice by Improving Mitochondrial Function via Interaction with NDUFA4
5个月前
已完结
PKM2 alleviates mitochondrial oxidative stress and neuronal apoptosis through metabolic and non-metabolic pathways to protect SOD1G93A mice
5个月前
已完结
Structural basis for the binding of DNP and purine nucleotides onto UCP1
6个月前
已完结
Micro-doses of DNP preserve motor and muscle function with a period of functional recovery in amyotrophic lateral sclerosis mice
6个月前
已完结
Arctigenin derivative a-1 ameliorates motor dysfunction and pathological manifestations in SOD1G93A transgenic mice via the AMPK/SIRT1/PGC-1α and AMPK/SIRT1/IL-1β/NF-κB pathways
6个月前
已完结
Impacts of pathogenic mutations on the structures of the CHCHD10 monomer: An AlphaFold3 study linked to the generation of conformational ensembles
6个月前
已完结
CHCHD2 and CHCHD10-related neurodegeneration: molecular pathogenesis and the path to precision therapy
6个月前
已完结
Pharmacological activation of mitophagy antagonizes motor neuron degeneration in a cross-species platform of amyotrophic lateral sclerosis
6个月前
已完结
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