Lv4
670 积分 2024-02-02 加入
Discovery ofHighly Potent and Selective, Orally BioavailableBTK-Targeting PROTACs Featuring Novel CRBN-Binding Warheads
1个月前
已完结
Rescuing dendritic cell interstitial motility sustains antitumour immunity
1个月前
已完结
Induced proximity-based therapeutic modalities
1个月前
已完结
Synthesis and biological evaluation of 5-carbamoyl-2-phenylpyrimidine derivatives as novel and potent PDE4 inhibitors
1个月前
已完结
Luvometinib: First Approval
1个月前
已完结
Molecular chameleons in drug discovery
2个月前
已完结
Discovery of a Highly Potent and Selective Tyrosine Kinase 2 (TYK2) Degrader with In Vivo Therapeutic Efficacy in a Murine Psoriasis Model
2个月前
已完结
Discovery of autophagy-tethering compounds as potent NLRP3 degraders for IBD Immunotherapy
2个月前
已完结
Degrading the key component of the inflammasome: development of an NLRP3 PROTAC
2个月前
已完结
Mechanisms and therapeutic strategies for NLRP3 degradation via post-translational modifications in ubiquitin-proteasome and autophagy lysosomal pathway
2个月前
已完结
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