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690 积分 2024-10-08 加入
Critical roles of IKAROS and HDAC1 in regulation of heterochromatin and tumor suppression in T-cell acute lymphoblastic leukemia
8小时前
已关闭
Targeting Activated Signaling Pathways for the Treatment of IKZF1-Deleted B Lymphoblastic Leukemia
1个月前
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Complete or Partial Deletions of IKZF1 Occur In 28% of Blast Crisis CML and Are the Only Recurrent Submicroscopic Alteration Associated with Disease Progression: An Analysis of 43 Cases Using High-Resolution Genome-Wide Copy Number DNA Arrays and Molecular Assays
2个月前
已关闭
Ikaros transcripts Ik6/10 and levels of full-length transcript are critical for chronic myeloid leukaemia blast crisis transformation
2个月前
已完结
Modeling IKZF1 lesions in B-ALL reveals distinct chemosensitivity patterns and potential therapeutic vulnerabilities
3个月前
已关闭
Givinostat, a type II histone deacetylase inhibitor, induces potent caspase-dependent apoptosis in human lymphoblastic leukemia
3个月前
已完结
Transcription factor Ikzf1 associates with Foxp3 to repress gene expression in Treg cells and limit autoimmunity and anti-tumor immunity
3个月前
已完结
Discovery of PRMT3 Degrader for the Treatment of Acute Leukemia
3个月前
已完结
Intrinsic signaling pathways modulate targeted protein degradation
3个月前
已完结
Apoptosis in Cancer Biology and Therapy
3个月前
已完结
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