Lv5
958 积分 2024-07-23 加入
Medicinal chemistry strategies targeting PRMT5 for cancer therapy
2个月前
已完结
MRTX1719 Is an MTA-Cooperative PRMT5 Inhibitor That Exhibits Synthetic Lethality in Preclinical Models and Patients with MTAP -Deleted Cancer
2个月前
已完结
In Situ Maleimide Bridging of Disulfides and a New Approach to Protein PEGylation
2个月前
已完结
One‐Step Assembly of Homogeneous DAR4 ADCs via a Traceless Fc Ligand‐Directed Acylation Strategy
3个月前
已完结
Natural products as payloads for antibody-drug conjugates: Cyclopamine linked to cetuximab for hedgehog pathway inhibition
3个月前
已完结
Research Progress on Small-molecule Inhibitors of Protein ArginineMethyltransferase 5 (PRMT5) for Treating Cancer
5个月前
已完结
PRMT5 inhibition by SCR-6920 downregulates HIF-1α and exhibits synergistic antitumor activity with bevacizumab in ovarian cancer
5个月前
已完结
Preclinical development of MGC028, an ADAM9-targeted, glycan-linked, exatecan-based antibody-drug conjugate for the treatment of solid cancers
6个月前
已完结
Site-Selective Anti-PD-L1 Antibody–MMAE Conjugate for Enhanced NSCLC Therapy
1年前
已完结
Targeting ATR in patients with cancer
1年前
已完结
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