Lv33
380 积分 2026-04-20 加入
Physiologically Based Pharmacokinetic Modeling of Oral Absorption, pH, and Food Effect in Healthy Volunteers to Drive Alpelisib Formulation Selection
1个月前
已完结
Antibody Conjugation of a Chimeric BET Degrader Enables in vivo Activity
2个月前
已完结
Small Molecule–Degrader Conjugates: Evaluating the Structure–Activity Relationship of Linkers to Overcome In Vivo Barriers in PROTAC Delivery
2个月前
已完结
Unexpected off-targeting effects of anti-huntingtin ribozymes and siRNA in vivo
2个月前
已完结
Safety Evaluation of CNS Administered Biologics—Study Design, Data Interpretation, and Translation to the Clinic
2个月前
已完结
Chemistry and formulations for siRNA therapeutics
2个月前
已完结
Engineering considerations for next-generation oligonucleotide therapeutics
2个月前
已完结
Evaluation of the distribution and excretion of [14C]-inclisiran following single subcutaneous administration in cynomolgus monkeys
3个月前
已完结
In vivo siRNA distribution and pharmacokinetics assessed by nuclear imaging are modulated according to radiolabelling site
3个月前
已完结
Development of a double-stranded siRNA labelling method by using99mTc and single photon emission computed tomography imaging
3个月前
已完结
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