Lv4
530 积分 2026-04-05 加入
The complexities of oligonucleotide therapeutics: analytical challenges and opportunities within early drug discovery
1个月前
已完结
Simultaneous quantification of siRNA antisense and sense strands by hybrid liquid chromatography-mass spectrometry
1个月前
已完结
Comparison of multiple bioanalytical assay platforms for the quantitation of siRNA therapeutics
1个月前
已完结
Optimizing sample preparation workflow for bioanalysis of oligonucleotides through liquid chromatography tandem mass spectrometry
2个月前
已完结
Improvement of serum sample preparation and chromatographic analysis of nusinersen used for the treatment of spinal muscular atrophy
3个月前
已完结
A New Precolumn Derivatization LC-MS/MS Method for the Determination of Methoxamine Enantiomers in Rat Plasma: Application to Stereoselective Pharmacokinetic Analysis
3个月前
已完结
Application of amino acid-based adsorbents for the extraction of antisense oligonucleotides from serum samples
3个月前
已完结
Automatic identification of oligonucleotide metabolites in complex biological samples using ultra high-performance liquid chromatography high-resolution mass spectrometry combined with the molecule profiler software
3个月前
已完结
A universal LC-HRMS workflow integrating targeted and untargeted strategies for rapid and comprehensive metabolite profiling of oligonucleotide-based therapeutics
3个月前
已完结
Development, Validation and Application of an Ion-Pair Reversed-Phase Liquid Chromatography-Tandem Mass Spectrometry Method for the Quantification of Nusinersen
3个月前
已完结
Life Before Speculum
4个月前
已采纳
The Future of Time: Methodological Dialogues between Philology, Archaeology, and Genomics
4个月前
已采纳
Disentangling the Phylogeny of Isoetes (Isoetales), Using Nuclear and Plastid Data
4个月前
已采纳
The End of the American Dream? Inequality and Segregation in US Cities
4个月前
已采纳
A Dual-Layer MOF Microneedle Patch for Self-Sensitized Mild Photothermal Therapy and Autophagy Regulation
4个月前
已采纳
Strain-modulated ultrafine bimetallic Au/Cu co-doped MoS2 nanoflower for highly selective detection of dopamine
4个月前
已采纳
How Cultural Diversity Drives Innovation: Surnames and Patents in US History
4个月前
已采纳
Targeting Semaphorin 7a signaling in preclinical models of endocrine therapy-resistant breast cancer
4个月前
已采纳
Prostate MRI Was Negative—What's Next?
4个月前
已采纳
Risk of Colorectal Cancer and Colorectal Cancer Mortality Beginning Ten Years after a Negative Colonoscopy, among Screen-Eligible Adults 76 to 85 Years Old
4个月前
已采纳
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