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42 积分 2022-08-31 加入
Precemtabart tocentecan, an anti-CEACAM5 antibody–drug conjugate, in metastatic colorectal cancer: a phase 1 trial
10天前
已完结
A total synthesis of dl-camptothecin
14天前
已完结
A New Strategy To Improve the Metabolic Stability of Lactone: Discovery of (20S,21S)-21-Fluorocamptothecins as Novel, Hydrolytically Stable Topoisomerase I Inhibitors
21天前
已完结
DNA Topoisomerase I Inhibitors: Chemistry, Biology, and Interfacial Inhibition
22天前
已完结
Aberrant bispecific antibody pharmacokinetics linked to liver sinusoidal endothelium clearance mechanism in cynomolgus monkeys
26天前
已完结
DX-8951f, a Hexacyclic Camptothecin Analog, on a Daily-Times-Five Schedule: A Phase I and Pharmacokinetic Study in Patients With Advanced Solid Malignancies
27天前
已完结
Total Synthesis of 7‐Ethyl‐10‐hydroxycamptothecin (SN38) and its Application to the Development of C18‐Functionalized Camptothecin Derivatives
1个月前
已完结
Experiments on the synthesis of dl-camptothecin. 4. Synthesis and antileukemic activity of dl-camptothecin analogues
1个月前
已完结
Loss of LGR5 through Therapy-induced Downregulation or Gene Ablation Is Associated with Resistance and Enhanced MET-STAT3 Signaling in Colorectal Cancer Cells
1个月前
已完结
Abstract 3996: The impact of HER3 dynamics on the efficacy of HER3-DXd, a novel HER3 directed antibody-drug conjugate
1个月前
已完结