Lv6
1870 积分 2022-09-21 加入
Discovery of 4-(((4-(5-chloro-2-(((1s,4s)-4-((2-methoxyethyl)amino)cyclohexyl)amino)pyridin-4-yl)thiazol-2-yl)amino)methyl)tetrahydro-2H-pyran-4-carbonitrile (JSH-150) as a novel highly selective and potent CDK9 kinase inhibitor
23天前
已完结
PRT2527, a Novel Highly Selective Cyclin-Dependent Kinase 9 (CDK9) Inhibitor, Has Potent Anti-Leukemic Activity in Preclinical Primary Models of Human B-ALL, T-ALL, and CLL
1个月前
已关闭
Induced proximity pushes beyond protein degraders, as first RIPTAC moves into the clinic
1个月前
已完结
TL1A Inhibition in Inflammatory Bowel Disease: A Pipeline Review
2个月前
已完结
TL1A blockade in inflammatory bowel diseases: Clinical trials to watch
2个月前
已完结
IRAK4 degrader to take on innate immunity
3个月前
已完结
Lessons from natural molecular glue degraders
4个月前
已完结
Fragment-based approaches to discover ligands for tumor-specific E3 ligases
4个月前
已完结
Ligands for cereblon: 2017–2021 patent overview
4个月前
已完结
Strengthening Molecular Glues: Design Strategies for Improving Thalidomide Analogs as Cereblon Effectors and Anticancer Agents
4个月前
已完结