Lv61
2510 积分 2022-08-25 加入
BRD4 inhibition induces synthetic lethality in ARID2-deficient hepatocellular carcinoma by increasing DNA damage
4小时前
已完结
EZH2 Cooperates with BRD4-NUT to Drive NUT Carcinoma Growth by Silencing Key Tumor Suppressor Genes
4小时前
已完结
Epigenetic Cooperativity as a Therapeutic Vulnerability in Cancer
5小时前
求助中
Design, synthesis and mechanism studies of dual EZH2/BRD4 inhibitors for cancer therapy
11小时前
已完结
BCL6 promotes a stem-like CD8 + T cell program in cancer via antagonizing BLIMP1
4天前
已完结
Design, Synthesis, and Biological Evaluation of a Potent Dual EZH2–BRD4 Inhibitor for the Treatment of Some Solid Tumors
7天前
已完结
Discovery of Highly Potent and Selective EZH2 Covalent Inhibitors via Incorporating Basic Amines
12天前
已完结
Chemically induced degradation of PRC2 complex by EZH2-Targeted PROTACs via a Ubiquitin-Proteasome pathway
12天前
已完结
Discovery of precision targeting EZH2 degraders for triple-negative breast cancer
12天前
已完结
A Facile Total Synthesis of Kilogram-Scale Production of SKLB1039: A Novel and Selective Hexahydroisoquinolin-Containing EZH2 Inhibitor
12天前
已完结
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