Lv3
380 积分 2025-03-21 加入
54020 Potent and selective TYK2 degraders, devoid of JAK activity, potently and completely suppress IL12/23 and IFN-a signaling pathways
1个月前
已关闭
Novel Small Molecule Tyrosine Kinase 2 Pseudokinase Ligands Block Cytokine-Induced TYK2-Mediated Signaling Pathways
1个月前
已完结
Design of a potent and selective dual JAK1/TYK2 inhibitor
1个月前
已关闭
Discovery of diaminopyrimidine-carboxamide derivatives as JAK3 inhibitors
1个月前
已完结
Design and synthesis of highly selective Janus kinase 3 covalent inhibitors for the treatment of rheumatoid arthritis
1个月前
已完结
THU0080 PRECLINICAL CHARACTERIZATION OF TLL018, A NOVEL, HIGHLY POTENT AND SELECTIVE JAK1/TYK2 INHIBITOR FOR TREATING AUTOIMMUNE DISEASES
1个月前
已完结
Deep seeking covalent DNA encoded library for novel JAK3 inhibitor discovery
1个月前
已完结
Targeting the Tyrosine Kinase 2 (TYK2) Pseudokinase Domain: Discovery of the Selective TYK2 Inhibitor ABBV-712
1个月前
已完结
Next-generation JAK inhibitors in the treatment of myeloproliferative neoplasms
1个月前
已完结
Synthesis of Stereoisomeric Analogues of Endomorphin-2, H-Tyr-Pro-Phe-Phe-NH2, and Examination of Their Opioid Receptor Binding Activities and Solution Conformation
1个月前
已完结
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