Lv6
2666 积分 2025-05-12 加入
A novel selective NLRP3 inhibitor shows disease-modifying potential in animal models of Parkinson’s disease
3个月前
已完结
B3Pdb: an archive of blood–brain barrier-penetrating peptides
3个月前
已完结
Ofirnoflast: a first-in-class NEK7-targeted inhibitor of the NLRP3 inflammasome
3个月前
已完结
Phase Ib Study Design Evaluating The Safety, Pharmacokinetics And Pharmacodynamics Of Selnoflast, A Novel NLRP3 Inflammasome Inhibitor In Early-Stage PD (P2-11.007)
3个月前
已关闭
Discovery of Clinical Candidate NT-0796, a Brain-Penetrant and Highly Potent NLRP3 Inflammasome Inhibitor for Neuroinflammatory Disorders
3个月前
已完结
Overcoming Preclinical Safety Obstacles to Discover (S)-N-((1,2,3,5,6,7-Hexahydro-s-indacen-4-yl)carbamoyl)-6-(methylamino)-6,7-dihydro-5H-pyrazolo[5,1-b][1,3]oxazine-3-sulfonamide (GDC-2394): A Potent and Selective NLRP3 Inhibitor
3个月前
已完结
A phase 2, proof-of-concept, placebo-controlled, randomized, multicenter, double-blind study to evaluate the efficacy, safety, tolerability, pharmacokinetics, and pharmacodynamics of Usnoflast (ZYIL1) in patients with amyotrophic lateral sclerosis
3个月前
已完结
Safety and Preliminary Efficacy of DFV890 in Adult Patients with Myeloid Diseases: A Phase 1b Study
3个月前
已关闭
Drugging the NLRP3 inflammasome: from signalling mechanisms to therapeutic targets
3个月前
已完结
Discovery of DFV890, a Potent Sulfonimidamide-Containing NLRP3 Inflammasome Inhibitor
3个月前
已完结
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