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44 积分 2025-03-19 加入
Janus kinase 2 activation mechanisms revealed by analysis of suppressing mutations
4小时前
已完结
Unraveling the secrets of novel PROTACs to improve degradation efficacy
13天前
已完结
Real-Time NanoBRET Target Engagement Reveals Permeability-Activity Relationships in BET-Targeting Degraders
19天前
已关闭
Contemporary design of small-molecule kinase modulators: orthosteric, allosteric and induced-proximity strategies
26天前
已完结
Safety considerations for cereblon-recruiting targeted protein degraders
1个月前
已完结
Nanoscale direct-to-biology optimization of Cdk2 inhibitors
1个月前
已完结
DNA-Encoded Library (DEL) Selection Identifies a Distinct DDB1 Ligand Binding Site
2个月前
已完结
Mechanism of homodimeric cytokine receptor activation and dysregulation by oncogenic mutations
2个月前
已完结
Mechanistic insights into Wnt–β-catenin pathway activation and signal transduction
3个月前
已完结
Subcellular localization as a driver of protein function
3个月前
已完结
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