Lv6
1906 积分 2023-07-04 加入
Recent progress in degradation of membrane proteins by PROTACs and alternative targeted protein degradation techniques
2天前
已完结
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation
2天前
已完结
A pomalidomide-based gefitinib PROTAC degrader effectively inhibits lung cancer progression in EGFR-TKIs-acquired resistant models by targeting EGFR degradation and ETFA-mediated ATP generation
2天前
已完结
Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions
3天前
已完结
Suppression of the hypothalamic–pituitary–gonadal axis by TAK-385 (relugolix), a novel, investigational, orally active, small molecule gonadotropin-releasing hormone (GnRH) antagonist: Studies in human GnRH receptor knock-in mice
19天前
已完结
Comparison of Fibrate, Ezetimibe, Low- and High-Dose Statin Therapy for the Dyslipidemia of the Metabolic Syndrome in a Mouse Model
20天前
已完结
The past, present, and future of ALK-targeted drug discovery
26天前
已完结
A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase
1个月前
已完结
Structural basis of lenalidomide-induced CK1α degradation by the CRL4CRBN ubiquitin ligase
1个月前
已完结
A multiprotein supercomplex controlling oncogenic signalling in lymphoma
1个月前
已完结
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