Lv61
3026 积分 2023-07-04 加入
Alymphoplasia is caused by a point mutation in the mouse gene encoding Nf-κb-inducing kinase
5小时前
待确认
A small-molecule VHL molecular glue degrader for cysteine dioxygenase 1
5天前
已完结
Human germline gain-of-function in STAT6: from severe allergic disease to lymphoma and beyond
1个月前
已完结
TRI-611, a selective, brain-penetrant molecular glue degrader of ALK
1个月前
已完结
A novel cereblon modulator recruits GSPT1 to the CRL4CRBN ubiquitin ligase
1个月前
已完结
Dual ALK and EGFR inhibition targets a mechanism of acquired resistance to the tyrosine kinase inhibitor crizotinib in ALK rearranged lung cancer
1个月前
已关闭
Discovery of Dotinurad (FYU-981), a New Phenol Derivative with Highly Potent Uric Acid Lowering Activity
1个月前
已完结
Crizotinib Reduces the Rate of Dark Adaptation in the Rat Retina Independent of ALK Inhibition
2个月前
已完结
Synthesis, Structure–Activity Relationships, and in Vivo Efficacy of the Novel Potent and Selective Anaplastic Lymphoma Kinase (ALK) Inhibitor 5‑Chloro‑N2‑(2-isopropoxy-5-methyl-4-(piperidin-4-yl)phenyl)‑N4‑(2-(isopropylsulfonyl)phenyl)pyrimidine-2,4-diamine (LDK378) Currently in Phase 1 and Phase 2 Clinical Trials
2个月前
已完结
Analysis of lorlatinib analogs reveals a roadmap for targeting diverse compound resistance mutations in ALK-positive lung cancer
2个月前
已完结