Lv65
2146 积分 2023-07-04 加入
Design and Development of DNA Damage Chemical Inducers of Proximity for Targeted Cancer Therapy
9天前
已完结
Hijacking ERAD for targeted degradation of transmembrane proteins
21天前
已完结
Mutant forms of EGFR promote HER2 trafficking through efficient formation of HER2-EGFR heterodimers
26天前
已完结
The effect of allergen-induced airway inflammation on airway remodeling in a murine model of allergic asthma
1个月前
已完结
A single domain antibody against the Cys- and His-rich domain of PCSK9 and evolocumab exhibit different inhibition mechanisms in humanized PCSK9 mice
1个月前
已完结
Enhanced HER2 internalization by clathrin-dependent endocytosis in non-small cell lung cancer positive for HER2 mutations
1个月前
已完结
Recent progress in degradation of membrane proteins by PROTACs and alternative targeted protein degradation techniques
1个月前
已完结
Design, Synthesis, and Biological Evaluation of Novel EGFR PROTACs Targeting C797S Mutation
1个月前
已完结
A pomalidomide-based gefitinib PROTAC degrader effectively inhibits lung cancer progression in EGFR-TKIs-acquired resistant models by targeting EGFR degradation and ETFA-mediated ATP generation
1个月前
已完结
Catalytic Degraders Effectively Address Kinase Site Mutations in EML4-ALK Oncogenic Fusions
1个月前
已完结